臨床神経学

<シンポジウム06―2>Brain-machine-interface はどこまで可能か?

Real-time NIRSによるニューロフィードバックをもちいた神経リハビリテーション

三原 雅史

社会医療法人大道会森之宮病院神経リハビリテーション研究部〔〒536―0025 大阪市城東区森之宮2―1―88〕

Recent advance in Brain-Machine interface (BMI) technology, including analysis of brain signal, enable a realtime interaction between patients and environment bypassing their damaged neuromuscular systems. Although most of researches have focused on substituting output function, it has been growing interest in applying this technology for restoring their brain. Several studies have proved that feedback of cortical activities (neurofeedback) enable regulating brain activation voluntarily. According to this notion, we have developed a real-time neurofeedback system mediated by near-infrared spectroscopy (NIRS) as a neurofeedback tool in neurorehabilitation. First, we have evaluated whether real-time cortical oxygenated hemoglobin (OxyHb) feedback signals correlated with reference OxyHb signals analyzed off-line during a motor execution task. Our results showed high correlation between results from two analyses. Second, we investigated whether the self-assessment scores for kinesthetic motor imagery and motor imagery related cortical activation was enhanced by neurofeedback. Our experiment with right handed healthy subjects revealed significant improvement of the imagery scale, and enhanced cortical activations including the contralateral premotor area. These results suggest that the neurofeedback technique may improve the efficacy of mental practice with motor imagery.
Full Text of this Article in Japanese PDF (213K)

(臨床神経, 51:924−926, 2011)
key words:リハビリテーション,運動想像,ブレイン―マシンインターフェース,近赤外分光法,ニューロフィードバック

(受付日:2011年5月19日)