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• Vol.64 No.1
• CLINICA NEUROL, 64: 1−7, 2024
• Vol.64 No.1 contents

Invited Review

Prospect of novel therapies in immune-mediated neuropathies

Motoi Kuwahara, M.D., Ph.D.

Department of Neurology, Kindai University Faculty of Medicine

The efficacy of immunotherapies such as steroids, plasmapheresis, and intravenous immunoglobulin have been proven in various immune-mediated neuropathies. However, these treatments sometimes lack the efficacy in a part of patients with the immune-mediated neuropathies. In addition, anti-myelin associated glycoprotein (MAG) neuropathy is usually refractory to the treatments. Recently, novel therapies targeting a molecule which are associated with pathogenesis of immune-mediated diseases, have been developed. These molecularly targeted therapies are notable in immunemediated neuropathies as novel drug candidates. In the present article, current treatments and future prospect of novel therapies in immune-mediated neuropathies will be reviewed.
Full Text of this Article in Japanese PDF (592K)

(CLINICA NEUROL, 64: 1−7, 2024)
key words: novel therapies, Guillain-Barré syndrome, chronic inflammatory demyelinating polyradiculoneuropathy, multifocal motor neuropathy, anti-MAG neuropathy

(Received: 12-May-23)