Rinsho Shinkeigaku (Clinical Neurology)

Case Report

A case of antepartum reversible cerebral vasoconstriction syndrome

Shiori Yamakawa, M.D.1), Kaori Kisimoto, M.D.2), Kuniyasu Wada, M.D.1), Yoichiro Hashimoto, M.D.1) and Mitsuharu Ueda, M.D., Ph.D.3)

1) Department of Neurology, Kumamoto City Hospital
2) Department of Obstetrics and Gynecology, Kumamoto City Hospital
3) Department of Neurology, Graduate School of Medical Sciences, Kumamoto University

A 35-year-old pregnant woman with mild migraine experienced thunderclap headache at 37 weeks of gestation. Her cerebral MRA showed arterial segmental narrowing of right middle cerebral artery and bilateral posterior cerebral artery. When admitted, she had no sign of eclampsia/preeclampsia. After 4 days, she had premature rupture of the membrane and gave birth by caesarean section. Caesarean section immediately resolved the headache. The postpartum course of the patient and her baby was uneventfull. One month after her onset, her cerebral MRA showed improvement in arterial segmental narrowing of cerebral artery. We diagnosed reversible cerebral vasoconstriction syndrome (RCVS) assoiated with pregnancy. Pregnancy-related RCVS develops primarily during the puerperal period, but our case was a rare case that developed just before delivery and was successful with aggressive intervention. When antepartum RCVS develops, early cesarean section with epidural anesthesia in parallel with active treatment for headache may lead to good outcomes for both mother and child.
Full Text of this Article in Japanese PDF (1365K)

(CLINICA NEUROL, 61: 681−686, 2021)
key words: thunderclap headache, reversible cerebral vasoconstriction syndrome, migraine, antepartum

(Received: 8-Apr-21)