Rinsho Shinkeigaku (Clinical Neurology)

Case Report

Amyloid β related angitis without marked leukoencephalopathy

Yoko Taniguchi, M.D.1), Taro Kitamura, M.D.1), Hiroyasu Inoue, M.D.1), Toshiyasu Miura, M.D., Ph.D.1) and Kentaro Yamada, M.D., Ph.D.1)

1)Department of Neurology, Nagoya City East Medical Center

An 86-year-old woman was admitted to our hospital with headache and acute detarioration of consciousness. Cerebral microbleeds (CMBs) dominated the occipital lobe on the head MRI, revealing white matter lesions. It was accompanied by gadolinium (Gd) imaging effect in the leptomeninges and some CMBs. She was clinically diagnosed with amyloid β-related vasculitis and a good outcome was obtained with steroid therapy. Even when symptoms re-exacerbated, exacerbation of the contrast effect of CMBs was observed, but no white matter lesions appeared, and leptomeningeal enhancement did not change remarkably throughout the entire course.
Full Text of this Article in PDF (527K)

(CLINICA NEUROL, 59: 814|817, 2019)
key words: cerebral amyloid angiopathy, CAA-RI, ABRA, leukoencephalopathy, anti-amyloid β antibody

(Received: 31-Jan-19)