Rinsho Shinkeigaku (Clinical Neurology)

The 49th Annual Meeting of the Japanese Society of Neurology

Toward a future Research in Neurology: molecular analysis of brain disorder

Katsuhiko Mikoshiba, M.D., Ph.D.

Lab. for Developmental Neurobiology Neuro-Developmental Disorder Research Group, RIKEN Brain Science Institute

Brain is highly organized organ important for learning and memory, emotion and behavior in social life. We are confronted to suffering from various brain disorders. I here present some of the research strategy for the analysis of brain disorder by molecular technique to find ways to cure the disorders. It is surprising to know that the important molecules involved in development and differentiation of the brain are all involved in the neurodegenerative disorder or neuropsychiatric disorders. I here stress the importance of the collaborative approach with other fields to analyze the brain structure and function at various levels at molecule-cell-tissue-organ-body-society.
Full Text of this Article in Japanese PDF (1019K)

(CLINICA NEUROL, 48: 815|820, 2008)
key words: molecule-cell-tissue-organ-body-society, neurological disease, psychiatric disease, mutant mice

(Received: 15-May-08)