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• Vol.55 No.9
• CLINICA NEUROL, 55: 646−650, 2015
• Vol.55 No.9 contents

Case Report

Cervical epidural β2-microglobulin amyloidoma presenting with acute paraplegia 5 months after introduction of hemodialysis

Eishun Nitta, M.D., Ph.D.¹⁾, Kenichi Sakajiri, M.D., Ph.D.¹⁾ and Atsuhiro Kawashima, M.D., Ph.D.²⁾

¹⁾Department of Neurology, National Hospital Organization Kanazawa Medical Center
²⁾Department of Pathology, National Hospital Organization Kanazawa Medical Center

A 66-year-old man was admitted to our hospital with acute paraplegia. He has suffered from hypertension with renal dysfunction for 7 years. Five months before admission, hemodialysis was introduced to him because of chronic renal failure due to renal sclerosis. One week before hospitalization, he noticed dizziness, sensory disturbance below the chest, and a urinary difficulty. Two days prior to admission, he could not walk independently. Spinal MRI revealed a mass at the 7th level of the cervical spine, showing low intensity on T₁-weighted image and surrounding hypointensity with inner mixed intensity on T₂-weighted image. An urgent surgery removed the cervical epidural mass and the following pathological evaluation established the diagnosis of β2-microglobulin amyloidoma. Hemodialysis-related amyloidoma generally emerges after a long duration of hemodialysis, demonstrates an insidious onset of symptoms, and is very rare. The current case indicates that we need to be aware of the possibility of β2-microglobulin amyloidoma even in patients with a short history of hemodialysis with a rapid presentation.
Full Text of this Article in Japanese PDF (1340K)

(CLINICA NEUROL, 55: 646−650, 2015)
key words: hemodialysis, β2-microglobulin, cervical amyloidoma, epidural

(Received: 26-Dec-14)