Mechanism of regional spread in ALS

May 30 (Thu)  9:00-9:50  Room4 (Hall B7 (2))

Chair:

Takanori Yokota

Department of Neurology and Neurological Science, Tokyo Medical and Dental University

Speaker:

John Ravits

University of California San Diego, USA

Advances in inherited neuropathies

May 31 (Fri)  9:00-9:50  Room4 (Hall B7 (2))

Chair:

Masanori Nakagawa

Kyoto Prefectural University of Medicine

Speaker:

Michael E Shy

Department of Neurology, University of Iowa Carver College of Medicine, Iowa, USA

Amyotrophic lateral sclerosis - What have we learned?

June 1 (Sat)  8:00-8:50  Room4 (Hall B7 (2))

Chair:

Satoshi Kuwabara

Chiba University

Speaker:

Matthew C. Kiernan

Neuroscience Research Australia and Prince of Wales Clinical School, University of New South Wales, Australia

Developing Neurology in the World

Chairs:

Ryuji Kaji	Department of Clinical Neuroscience, Institute of Health Biosciences, The University of Tokushima Graduate School
Raad Shakir	Imperial College NHS Trust, Charing Cross Hospital, London, UK / World Federation of Neurology

The Japanese Society of Neurology and developing neurology in the world

Speaker:

Hidehiro Mizusawa

Meeting President, the 54th Annual Meeting of the Japanese Society of Neurology/President/CEO, the Japanese Society of Neurology/Department of Neurology and Neurological Science, Tokyo Medical and Dental University

Developing neurology in the world
WFN/European view

Speaker:

Raad Shakir

Imperial College NHS Trust, Charing Cross Hospital, London, UK / World Federation of Neurology

Developing neurology in Asia and Oceania

Speaker:

Man Mohan Mehndiratta
	Asian Oceanian Association of Neurology (AOAN), World Federation of Neurology, India

The Panamerican Federation of Neurological Societies a WFN Initiative and Neurology in the Central America

Speaker:

Marco T. Medina

Facalty of Medical Sciences, National Autonomous University of Honduras, Honduras

The development of neurology in Central and South America

Speaker:

Renato J. Verdugo

Service of Neurology, Faculty of Medicine, Clinica Alemana-Universidad del Desarrollo, Santiago, Chile

Spinocerebellar Ataxia: Research Progress and Developing Treatment

Chairs:

Hidehiro Mizusawa	Department of Neurology and Neurological Science, Tokyo Medical and Dental University
Tetsuo Ashizawa	McKnight Brain Institute, University of Florida, USA

SCA13 and channel disorders

Speaker:

Stefan-M. Pulst

University of Utah, Salt Lake City, USA

Toward understanding an treating the polyglutamine ataxia spinocerebellar ataxia type 3 (SCA3)

Speaker:

Henry Paulson

Department of Neurology, University of Michigan, USA

Spinocerebellar ataxia type 31 (SCA31) and non-coding repeat expansion disorders

Speaker:

Kinya Ishikawa

Department of Neurology and Neurological Science, Tokyo Medical and Dental University

Multiple system atrophy (MSA)

Speaker:

Shoji Tsuji

Neuroscience, Graduate School of Medicine, The University of Tokyo

Cerebral Small Vessel Disease -Up to Date-

Chairs:

Shinichiro Uchiyama	Department of Neurology, Tokyo Women's Medical University
Reinhold Schmidt	University Clinic of Neurology, Clinical Division of Neurogeriatrics, Medical University Graz, Austria

An overview on recent advances in age-related cerebral small vessel disease

Speaker:

Reinhold Schmidt

University Clinic of Neurology, Clinical Division of Neurogeriatrics, Medical University Graz, Austria

CADASIL, recent progress

Speaker:

Anne Joutel

INSERM, University of Paris, France

An emerging molecular mechanism for the cerebral small vessel disease

Speaker:

Osamu Onodera

Department of Molecular Neuroscience, Resource Branch for Brain Disease, Brain Research Institute, Niigata University

Oral Session

Spinocerebellar Ataxias and Related Disorders in East Asia

Chairs:

Ching Piao Tsai	The Neurological Institute, Veterans General Hospital, Taipei, Taiwan
Hidenao Sasaki	Hokkaido University, Graduate School of Medicine / School of Medicine

SCA6: Lessons from genetic mouse models

Speaker:

Kei Watase

Center for Brain Integration Research, Tokyo Medical and Dental University

Movement Disorders in spinocerebellar ataxias

Speaker:

Beom S. Jeon

Department of Neurology, College of Medicine, Seoul National University, Korea

Identification of TGM6 as a novel causative gene of SCA35 and its implication for pathogenesis

Speaker:

Bei-sha Tang

Department of Neurology, Xiangya Hospital, Central South University / Neurodegenerative Disorders Research Center, Central South University / State Key Lab of Medical Genetics, Central South University, Changsha, Hunan, China

Mutations in KCND3 cause spinocerebellar ataxia type 22

Speaker:

Bing-wen Soong

Dept of Neurology, National Yang-Ming University School of Medicine, Taipei, Taiwan

Poster Session

Chair:

Hidenao Sasaki

Hokkaido University, Graduate School of Medicine

Using Next-Generation Sequencing as a genetic diagnostic tool in rare autosomal recessive neurological Mendelian disorders

Speaker:

Hong Jiang

Department of Neurology, Xiangya Hospital, Central South University, Changsha, Hunan, China / Neurodegenerative Disorders Research Center, Central South University, Changsha, Hunan, China

Mutations in GNB4 cause Dominant Intermediate Charcot-Marie-Tooth disease

Speaker:

Yi-Chung Lee

Department of Neurology, Taipei Veterans General Hospital / Department of Neurology, National Yang-Ming University, Taipei, Taiwan

Comprehensive genetic analysis of autosomal dominant spinocerebellar ataxia using a next generation sequencer

Speaker:

Yujiro Higuchi

Department of Neurology and Geriatrics, Kagoshima University Graduate School of Medical and Dental Science

Analysis of autosomal dominant spinocerebellar ataxias using Next-Generation sequencing

Speaker:

Kokoro Ozaki

Department of Neurology and Neurological Science, Tokyo Medical and Dental University

Structural Template for Neurodegeneration -From Network to Clinical Manifestations-

May 30 (Thu)  10:00-11:50  Room10 (G502)

Chairs:

Shigeo Murayama	The Brain Bank for Aging Research of Tokyo Metropolitan Healthy Longevity Medical Center
Toshiki Uchihara	Laboratory of Structural Neuropathology, Tokyo Metropolitan Institute of Medical Science

Neuroanatomy of regional progression in the human brain and spinal cord

Speaker:

Kelly Del Tredici-Braak
	Clinical Neuroanatomy Section, Department of Neurology, Center for Biomedical Research, University of Ulm, Ulm, Germany

Axonal α-synuclein and dendritic tau: contrasting spreads in neurons

Speaker:

Toshiki Uchihara

Laboratory of Structural Neuropathology, Tokyo Metropolitan Institute of Medical Science

Transmission and propagation of tau pathology in transgenic mouse brain

Speaker:

Markus Tolnay

Institute of Pathology, Basel University Hospital, Basel, Switzerland

Basics of Epilepsy Treatment and Advances of Seizure Focus Localization

May 31 (Fri)  13:30-15:20  Room6 (Hall B5 (2))

Chairs:

Sadatoshi Tsuji	International University of Health and Welfare
Akio Ikeda	Department of Neurology, Kyoto University Hospital and Graduate School of Medicine

Current antiepileptic treatment in women of child-bearing age

Speaker:

Torbjörn Tomson

Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden

Routine scalp EEG: The diagnostic role in epilepsy

Speaker:

Ayumu Onuma

Department of Neurology, Kohnan Hospital

Usefulness of long term video EEG monitoring and factors for consideration

Speaker:

Hiroshi Shigeto

Fukuoka Sanno Hospital

Progress in functional neuroimaging of epilepsy

Speaker:

Hiroshi Matsuda

Integrative Brain Imaging Center, National Center of Neurology and Psychiatry

Pathogenesis and Treatment of NMO

May 31 (Fri)  13:30-15:20  Room7 (Hall D7)

Chairs:

Yasuto Itoyama	National Center Hospital, National Center of Neurology and Psychiatry
Makoto Matsui	Department of Neurology, Kanazawa Medical University

Clinical spectrum of NMO: How broad is it?

Speaker:

Brian G. Weinshenker
	Department of Neurology, Mayo Clinic, Rochester MN, USA

Neuropathology of NMO: a nosological consideration

Speaker:

Kazuo Fujihara

Department of MS Therapeutics, Tohoku University Graduate School of Medicine

NMO pathogenesis mechanisms and new therapeutic approaches

Speaker:

Alan S. Verkman

University of California, San Francisco, USA

Gene Silencing Therapy for Neurological Diseases

May 31 (Fri)  13:30-15:20  Room9 (Hall D1)

Chairs:

Beverly L. Davidson	Department of Neurology, University of Iowa, USA
Shinichi Takeda	National Center of Neurology and Psychiatry

RNAi medicine for the brain

Speaker:

Beverly L. Davidson

University of Iowa, Iowa, USA

Advances in RNA interference (RNAi) therapeutics

Speaker:

Muthiah Manoharan

Alnylam Pharmaceuticals, Cambridge, MA, USA

Antisense oligonucleotide therapies for the treatment of neurodegenerative diseases

Speaker:

C. Frank Bennett

Isis Pharmaceuticals Inc., USA

Recent Progress in Multiple System Atrophy

May 31 (Fri)  13:30-15:20  Room13 (G701)

Chairs:

Hideki Mochizuki	Department of Neurology, Osaka University Graduate School of Medicine
Atsushi Takeda	Department of Neurology, Tohoku University School of Medicine

Pathogenesis of multiple system atrophy

Speaker:

Takafumi Hasegawa

Department of Neurology, Tohoku University School of Medicine

Genetics from familial multiple system atrophy

Speaker:

Jun Goto

Department of Neurology, The University of Tokyo Hospital

Neuroimaging of multiple system atrophy

Speaker:

A. Jon Stoessl

The Pacific Parkinson's Research Centre and National Parkinson Foundation Centre of Excellence at UBC & Vancouver Coastal Health, Canada

Vascular Dementia and Its Associated Conditions -Vascular Cognitive Impairment (VCI)

June 1 (Sat)  8:00-9:50  Room6 (Hall B5 (2))

Chairs:

Hidekazu Tomimoto	Department of Neurology, Mie University Graduate School of Medicine
Osamu Onodera	Department of Molecular Neuroscience, Resource Branch for Brain Disease, Brain Research Institute, Niigata University

Overview of the neuropathology of vascular cognitive disorders

Speaker:

Raj N Kalaria

Institute for Ageing and Health, NIHR Biomedical Research Building, Newcastle University, Newcastle upon Tyne, UK

Chronic cerebral hypoperfusion and dementia

Speaker:

Kenichiro Yata

Department of Neurology, Mie University Graduate School of Medicine

Cerebral amyloid angiopathy and cognitive impairment

Speaker:

Masafumi Ihara

Department of Stroke and Cerebrovascular Diseases, National Cerebral and Cardiovascular Center

Vascular cognitive impairment (VCI) and gene

Speaker:

Atsushi Watanabe

National Center for Geriatrics and Gerontology, Laboratory of Research Advancement

Non-coding Repeat Expansion Disorders

June 1 (Sat)  8:00-9:50  Room9 (Hall D1)

Chairs:

Kinji Ohno	Division of Neurogenetics, Nagoya University Graduate School of Medicine
Tohru Matsuura	Department of Neurology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences

Repeat-associated diseases, mutagenesis, pathogenesis, and therapeutic avenues

Speaker:

Christopher E. Pearson
	The Reasearch Institute, The Hospital for Sick Children, Toronto, Canada

Spinocerebellar ataxia type 31

Speaker:

Kinya Ishikawa

Department of Neurology and Neurological Science, Tokyo Medical and Dental University

Clinical features of novel ALS/SCA crossroad mutation Asidan (SCA36)

Speaker:

Koji Abe

Department of Neurology, Okayama University

Found in translation: Novel disease mechanisms in Fragile X Tremor Ataxia Syndrome

Speaker:

Peter K. Todd

The Bucky and Patti Harris Professor of Neurology, University of Michigan Medical School, USA