Rinsho Shinkeigaku (Clinical Neurology)

Brief Clinical Note

A rare case of Streptococcus salivarius meningitis in elderly

Daisuke Kuzume, M.D.1), Yuko Morimoto, M.D.1), Masato Kinboshi, M.D., Ph.D1), Takeshi Yoshida, M.D.2) and Masahiro Yamasaki, M.D.1)

1)Department of Neurology, Chikamori Hospital
2)Department of Reumatology, Chikamori Hospital

An 80-year-old man who had chronic heart failure and atrial fibrillation was refered to our hospital because of acute onset of fever and consciousness disturbance. Neurological examinations revealed deteriorated consciousness, nuchal rigidity and Kernig's sign. A lumber puncture yielded clouded fluid with a WBC 11,200/µl (polynuclear cell 94%), 758 mg/dl of protein, 1 mg/dl of glucose, 0.007 of cerebrospinal fluid-blood glucose ratio and Gram positive cocci. Diffusionweighted images on brain MRI showed no signal intensity in bilateral ventricles at admission. He was treated with ceftriaxon, vancomycin and ampicillin. Streptococcus salivarius (S. salivarius) was isolated from blood and cerebrospinal fluid. He responded promptly to antibiotics therapy, and within 5 days, he became lucid and afebrile. S. salivarius was sensitive for ceftriaxone, vancomycin and ampicillin. After Day 6, he was treated with ceftriaxone only. We diagnosed his condition as S. salivarius meningitis. He discharged from our hospital at Day 22. Many cases of S. salivarius meningitis were occurred in second and fifth decade. But elderly case was rare. Neurologist should consider that elderly case with bacterial meningitis was caused by S. salivarius.
Full Text of this Article in Japanese PDF (406K)

(CLINICA NEUROL, 59: 371|374, 2019)
key words: elderly, bacterial meningitis, Strptococcus salivarius

(Received: 18-Feb-19)