Rinsho Shinkeigaku (Clinical Neurology)

Brief Clinical Note

Devotion to painting in a Parkinson's disease patient

Nozomu Matsuda, M.D., Ph.D.1), Shunsuke Kobayashi, M.D., Ph.D.1) and Yoshikazu Ugawa, M.D., Ph.D.1)2)3)

1)Department of Neurology, Fukushima Medical University
2)Department of Neural Regeneration, Fukushima Medical University
3)Department of Neurology, Aidu Chuo Hospital

We report a 77-year-old man who suffered from Parkinson's disease for 12 years. Four years after the disease onset, he started to show excessive hobbyism of painting. His painting skills improved along with escalating enthusiasm. He even held a personal exhibition of his paintings. Dopaminergic treatment was increased as he developed wearing-off phenomenon. Six years after the disease onset, he developed dopamine dysregulation syndrome (DDS). In the same year, he underwent surgery for subthalamic deep brain stimulation. DDS did not improve and he did not lose enthusiasm for painting after surgery. Switching from ropinirole to rotigotine improved the DDS, but did not affect the excessive enthusiasm. At the age of 76, he started to have difficulty in completing the paintings. He had an uncontrollable urge to overlay paint strokes until the colors blurred and the paper was torn. In neuropsychological examinations, Mini-Mental State Examination score was above the cutoff, but Frontal Assessment Battery suggested motor perseveration and disinhibition. In summary, the patient's excessive enthusiasm for painting emerged in association with impulse control disorder (ICD) by dopamine agonist therapy, and subsequent change in his painting style appeared to be related with motor perseveration and/or further escalation of ICD.
Full Text of this Article in Japanese PDF (486K)

(CLINICA NEUROL, 58: 756|760, 2018)
key words: Parkinson's disease, art, impulse control disorder, frontal dysfunction

(Received: 28-Apr-18)