Rinsho Shinkeigaku (Clinical Neurology)

Brief Clinical Note

Symmetrical lesions of the cerebral peduncles and internal capsules on MRI in a patient with extranodal NK/T cell lymphoma

Yuko Takeuchi, M.D., Ph.D.1)2), Tomotsugu Kaga, M.D.1), Miho Ieda, M.D.3), Yumi Kojima, M.D., Ph.D.3), Jun Ochiai, M.D., Ph.D.1) and Chiyuki Mabuchi, M.D., Ph.D.1)

1)Department of Neurology, Nagoya Ekisaikai Hospital
2)Present Address: Department of Neurology, Masuko Memorial Hospital
3)Department of Haematology, Nagoya Ekisaikai Hospital

A 72-year-old man was admitted to our hospital because of subacute progressive consciousness disturbance. FLAIR images showed diffuse high intensity areas in the bilateral thalamus, basal ganglia, and white matter. Chest CT revealed a mass in the right lung. The patient was diagnosed with extranodal natural killer/T cell lymphoma (ENKL) according to the results of a biopsy of the right pulmonary mass. The FLAIR images showed diffuse white matter lesions, without a mass such as lymphomatosis cerebri. On diffusion-weighted images, symmetrical high-intensity lesions of the cerebral peduncle and the internal capsule suggested high-density lymphoma cells around neurons. ENKL of the central nervous system and lung is a very rare neoplasm, and this case showed characteristic images.
Full Text of this Article in Japanese PDF (684K)

(CLINICA NEUROL, 57: 778|781, 2017)
key words: extranodal NK/T cell lymphoma, lymphomatosis cerebri, diffusion weighted image, pulmonary malignant lymphoma, Epstein-Barr virus

(Received: 27-Jun-17)