Rinsho Shinkeigaku (Clinical Neurology)

Brief Clinical Note

67Ga scintigraphy as a therapeutic marker for spinal cord and muscular sarcoidosis: A case report

Shinichiro Yamada, M.D.1), Hirotaka Nakanishi, M.D.1), Masaaki Hirayama, M.D.1), Masahisa Katsuno, M.D.1) and Gen Sobue, M.D.1)

1)Department of Neurology, Nagoya University Graduate School of Medicine

A 70-year-old woman was admitted to our hospital because of the right limb pain and gait disturbance. 67Ga scintigraphy showed an increased uptake in the spinal cord, mediastinal lymph node and right tibialis anterior muscle. Based on the histopathological findings of epithelioid cell granuloma in endobronchial ultrasound-guided transbronchial needle aspiration of lymph node, she was diagnosed as having probable spinal cord/muscular sarcoidosis. After she was treated with oral prednisolone, her limb pain and gait disturbance improved. Furthermore, uptake in 67Ga scintigraphy was reduced after the treatment. In conclusion, 67Ga scintigraphy is useful not only for diagnosis, but also for estimating the efficiency of the treatment for sarcoidosis involving multiple organs such as the spinal cord and skeletal muscle.
Full Text of this Article in Japanese PDF (1237K)

(CLINICA NEUROL, 55: 665|668, 2015)
key words: neurosarcoidosis, spinal cord sarcoidosis, muscular sarcoidosis, 67Ga scintigraphy, therapeutic marker

(Received: 5-Mar-15)