Rinsho Shinkeigaku (Clinical Neurology)

Case Report

Medial longitudinal fasciculus (MLF) syndrome in a patient with giant cell arteritis

Takeshi Uenaka, M.D.1), Hirotoshi Hamaguchi, M.D., Ph.D.2), Kenji Sekiguchi, M.D., Ph.D.1), Hisatomo Kowa, M.D., Ph.D.1), Fumio Kanda, M.D., Ph.D.1) and Tatsushi Toda, M.D., Ph.D.1)

1)Division of Neurology, Kobe University Graduate School of Medicine
2)Division of Neurology, Kita-Harima Medical Center

A 76-year-old female was referred to our department because of diplopia for two months and intermittent claudication for five months. She showed medial longitudinal fasciculus (MLF) syndrome. Brain MRI (T2WI) showed multiple infarctions in the right pontine tegmentum and left paramedian midbrain. A biopsy of superficial temporal artery showed the characteristic findings of glanulomatous inflammation indicative of giant cell arteritis. We thought the mechanism of this cerebral infarction as artery to artery embolization or intracranial arteritis. Treatment with oral prednisolone (1 mg/kg/day) improved her limb claudication and normalized serum C-reactive protein level.
Full Text of this Article in Japanese PDF (734K)

(CLINICA NEUROL, 55: 107|110, 2015)
key words: giant cell arteritis, medial longitudinal fasciculus (MLF) syndrome, cerebral infarction, temporal arteritis

(Received: 24-Jun-14)