Rinsho Shinkeigaku (Clinical Neurology)

Brief Clinical Note

A case of acute limbic encephalitis with cerebral salt wasting syndrome

Motonobu Nishio, M.D.1), Nobuyuki Nishitani, M.D.1) and Keiko Tanaka, M.D.2)

1)Department of Neurology, Bell Land General Hospital
2)Department of Neurology, Kanazawa Medical University

A 37-year-old woman presented with psychiatric symptoms. Cerebrospinal fluid analysis revealed pleocytosis and increased protein. The patient was diagnosed with limbic encephalitis on the basis of the clinical course. However, remarkable hyponatremia was noted throughout the clinical course, leading to a diagnosis of cerebral salt wasting syndrome (CSWS). The hyponatremia was alleviated by supplementation with sodium and water. The findings seen in this case indicate that differentiation between syndrome of inappropriate of antidiuretic hormone and CSWS is important in cases of hyponatremia accompanied by central nervous system disease.
Full Text of this Article in Japanese PDF (1364K)

(CLINICA NEUROL, 54: 657|659, 2014)
key words: limbic encephalitis, cerebral salt wasting syndrome, SIADH, hyponatremia

(Received: 18-Sep-13)