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• Vol.51 No.11
• CLINICA NEUROL, 51: 868−871, 2011
• Vol.51 No.11 contents

Educational Lecture 14

Significance of COI disclosure in medical research in Japan

Saburo Sone, M.D.

JA Kochi Hospital
COI Committee of the Japanese Association of Medical Science

In medical research, remarkable increase in collaboration with industry, public organizations such as universities, research institutions, and academic societies makes researchers to be more deeply involved with the activities of commercial entities. Activities of education and research, which are the responsibilities of academic institutions and societies, conflict with the interests of individuals associated with industrial-academic collaboration. Management of such conflict of interest (COI) is of much importance for academic institutions and societies to appropriately promote industrial-academic collaborative activities. Particularly, participation not only by healthy individuals, but also patients, is essential in the medical field as subjects of clinical research. For those involved in medical research, the deeper the level of COI with commercial entities, who are the financial or benefit provider, becomes serious, the more human rights of subjects could be violated, safety of life could be endangered, and research methods, data analysis and interpretation of results could be distorted. It is also possible that research may be unfairly evaluated or not published, even if the results are accurate, sometimes resulting in the ascertained effects of reporting bias included the overestimation of efficacy and the underestimation of safety risks of interventions. According to the COI management guideline of the Japanese Association of Medical Science (JAMS), significance of COI management is discussed.
Full Text of this Article in Japanese PDF (393K)

(CLINICA NEUROL, 51: 868−871, 2011)
key words: COI, conflict of interest, medical research, academia-industry collaboration

(Received: 20-May-11)