Rinsho Shinkeigaku (Clinical Neurology)

The 51st Annual Meeting of the Japanese Society of Neurology

Intrathecal baclofen therapy

Takaomi Taira, M.D.

Department of Neurosurgery, Tokyo Women's Medical University

Intrathecal baclofen therapy (ITB) is a surgical treatment of spasticity by administrating small amount of baclofen directly into the spinal intrathecal space. This has been developed over the past twenty years, and now it is a well-established procedure. Indication of ITB is otherwise intractable severe spasticity of cerebral or spinal origin. Although the antispastic effect is dramatic, troubles regarding the catheter system is not rare, which may cause withdrawal syndrome. Therefore careful and close follow-up system is indispensable.
Full Text of this Article in Japanese PDF (416K)

(CLINICA NEUROL, 50: 816|819, 2010)
key words: baclofen, spasticity, intrathecal administration, target therapy

(Received: 20-May-10)