Rinsho Shinkeigaku (Clinical Neurology)

Brief Clinical Note

A case of transient cortical blindness due to thrombosis of the transverse sinus

Shingo Mitaki, M.D., Hitoshi Fukuda, M.D., Ph.D. and Mitsuhiro Kitani, M.D., Ph.D.

Department of Neurology, Masuda Red Cross Hospital

An 62-year-old man presented visual impairment and generalized seizure. Brain CT performed on the day of admission showed thrombus in the right transverse sinus, and DWI showed high intensity areas in the bilateral occipital and parietal lobes. According to bilateral occipital lobe lesions, we considered his visual impairment as cortical blindness. He was diagnosed as venous sinus thrombosis and intravenous heparin, edaravone and osmotic diuretics were administered. MR venography performed after starting of intravenous treatment showed flow gap in the left transverse sinus but no abnormalities in the right transverse sinus. On the second day of hospitalization, his cortical blindness showed improvement and thrombus in the right transverse sinus were disappeared. This indicated that his left transverse sinus originally hypoplastic, thrombus and hemostatis in the right transverse sinus (his dominant side) caused his cortical blindness and generalized seizure. There was a recanalization in the right transverse sinus after heparin therapy.
Full Text of this Article in Japanese PDF (520K)

(CLINICA NEUROL, 48: 351|354, 2008)
key words: sinus thrombosis, cortical blindness, cerebral infarction, seizure, MR venography

(Received: 29-Sep-07)