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  会員専用

• ホーム
• 52巻11号
• 臨床神経, 52：1182−1184, 2012
• 52巻11号目次

＜シンポジウム（2）―12―3＞リハビリテーションからみた神経回路の可塑性とBMI

一次運動野刺激と大脳皮質再構築

齋藤　洋一, 細見　晃一, 圓尾　知之

大阪大学産学連携本部脳神経制御外科学〔〒565―0871 大阪府吹田市山田丘2―1〕

The use of electrical motor cortex stimulation (EMCS) for post-stroke pain was established in Japan and has spread globally. EMCS has been used for the treatment of neuropathic pain, Parkinson's syndrome, and recovery of motor paresis. Since 2000, repetitive transcranial magnetic stimulation (rTMS) has been developed for the treatment of various neurological disorders. rTMS is a non-invasive method with almost no adverse effects. In the USA, rTMS of the left dorsolateral prefrontal cortex was approved for the treatment of major depression in 2008. rTMS of the primary motor cortex (M1) has been studied worldwide for the treatment of neuropathic pain, Parkinson's disease, motor paresis after stroke, and other neurological problems. For neuropathic pain, highfrequency rTMS of M1 is safe and significantly effective for consecutive 14 days. After cessation of rTMS, pain gradually returned within two weeks. For `Kaifukuki' rehabilitation, high-frequency rTMS of affected M1 seemed to be effective for recovery of hand function. And even after cessation of rTMS, the recovery would be better than usual rehabilitation for two weeks. New methods and devices for rTMS therapy are under development, and rTMS of the M1 is likely to be established as an effective therapy for some neurological disorders.
Full Text of this Article in Japanese PDF (245K)

(臨床神経, 52：1182−1184, 2012)
key words：一次運動野，反復経頭蓋磁気刺激，神経障害性疼痛，リハビリテーション

（受付日：2012年5月24日）