臨床神経学

<シンポジウム31―3>片頭痛の慢性化,難治化のメカニズムと治療

難治性薬物乱用頭痛の治療

濱田 潤一

北里大学神経内科学〔〒252―0374 神奈川県相模原市南区北里1―15―1〕

Medication overuse headache (MOH) is refractory headache with continuous and large amount use of drugs (analgesics, non-steroidal anti-inflammatory drugs, and triptans etc.) For treatment of MOH, overused drugs must be stopped as soon as possible. And preventive medication should be started at the same time. Also, the history of the patient's headache and social condition must be clarified. In some cases, replacement therapy with another medication must be considered. But, even in recent years, scientific research in high-evidence level cannot be achieved. We should make more clear animal models of MOH and the investigations with more basic study must be scheduled.
Full Text of this Article in Japanese PDF (190K)

(臨床神経, 51:1150−1152, 2011)
key words:片頭痛,緊張型頭痛,薬物乱用頭痛,治療

(受付日:2011年5月20日)